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KMID : 0545120070170050865
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Journal of Microbiology and Biotechnology
2007 Volume.17 No. 5 p.865 ~ p.867
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Redoxcitrinin, a Biogenetic Precursor of Citrinin from Marine Isolate of Fungus Penicillium sp
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Zhang Dahai
Li Xianguo
Kang Jung-Sook
Choi Hong-Dae
Jung Jee-H.
Son Byeng-Wha
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Abstract
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A chemical analysis of the fermentation of the marine-derived fungus Penicillium sp. led to the isolation of a biogenetic precursor of citrinin, redoxcitrinin (1), together with polyketide mycotoxins, phenol A (2), citrinin H2 (3), 4- hydroxymellein (4), citrinin (5), and phenol A acid (6). The structures of compounds 1-6 were determined on the basis of physicochemical data analyses. Among them, compounds 1- 3 exhibited a potent radical scavenging activity against 1,1- diphenyl-2-picrylhydrazyl (DPPH) with IC50 values of 27.7, 23.4, and 27.2 μM, respectively
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KEYWORD
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Marine-derived fungus, Penicillium sp., redoxcitrinin, biogenetic precursor, citrinin, polyketide
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